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Tumors Information

A tumor or tumour is the name for a neoplasm or a solid lesion formed by an abnormal growth of cells (termed neoplastic) which looks like a swelling.[1] Tumor is not synonymous with cancer. A tumor can be benign, pre-malignant or malignant, whereas cancer is by definition malignant.

Contents

Etymology

The term tumour/tumor is derived from the Latin word for "swelling" tumor and has come to the English language via the Old French tumour (contemporary French: tumeur). In the Commonwealth the spelling "tumour" is commonly used, whereas in the U.S. it is usually spelled "tumor".

In its medical sense it originally meant an abnormal swelling of the flesh. Celsus (ca 30 BC–38 AD) described four cardinal signs of acute inflammation as tumor, dolor, calor and rubor (swelling, pain, increased heat and redness).

But in contemporary English, tumor is synonymous with solid neoplasm,[2] all other forms of swelling being called swelling.[3] This usage is common also in medical literature, where the nouns tumefaction and tumescence, derived from the adjective tumefied, are the current medical terms for non-neoplastic swelling. Swelling is most often caused by inflammation caused by trauma, infection, etc.

Cause

A. Normal pathway. B. Daughter cell fails to proliferate causing a tumor. C. Stem cell fails to create a daughter cell and keeps dividing causing a tumor.

A neoplasm is an abnormal proliferation of tissues, usually caused by genetic mutations. Most neoplasms cause a tumor, with a few exceptions like leukemia or carcinoma in situ.

The nature of the tumor is determined by a pathologist after examination of the tumor tissues from a biopsy or a surgical excision specimen and is then qualified as benign, pre-malignant or malignant.

References

Neurofibroma

  1. ^ Tumor at Dorland's Medical Dictionary
  2. ^ Tumor in MedlinePlus Medical Encyclopedia
  3. ^ Swelling in MedlinePlus Medical Encyclopedia

See also

External links

Look up tumor or tumour in Wiktionary, the free dictionary.
Pathology: Tumor, Neoplasm, Cancer, and Oncology (C00–D48, 140–239)
Conditions
Benign tumors Hyperplasia · Cyst · Pseudocyst · Hamartoma
Malignant progression Dysplasia · Carcinoma in situ · Cancer · Metastasis
Topography Head/Neck (Oral, Nasopharyngeal) · Digestive system · Respiratory system · Bone · Skin · Blood · Urogenital · Nervous system · Endocrine system
Histology Carcinoma · Sarcoma · Papilloma · Adenoma
Other Precancerous condition · Paraneoplastic syndrome
Staging/grading TNM · Ann Arbor · Prostate cancer staging · Gleason Grading System · Dukes classification
Carcinogenesis Cancer Cells · Carcinogen · Tumor suppressor genes/oncogenes · Oncovirus · Cancer bacteria
Misc. Research · List of oncology-related terms

: NEO

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drug (//)

Inflammation
Acute
Plasma derived mediators Bradykinin · complement (C3, C5a, MAC) · coagulation (Factor XII, Plasmin, Thrombin)
Cell derived mediators preformed: Lysosome granules · vasoactive amines (Histamine, Serotonin) synthesized on demand: cytokines (IFN-γ, IL-8, TNF-α, IL-1) · eicosanoids (Leukotriene B4, Prostaglandins) · Nitric oxide · Kinins
Chronic Macrophage · Epithelioid cell · Giant cell · Granuloma
Processes Traditional: Rubor · Calor · Tumor · Dolor (pain) · Functio laesa Modern: Acute-phase reaction/Fever · Vasodilation · Increased vascular permeability · Exudate · Leukocyte extravasation · Chemotaxis
Specific types
Nervous CNS (Encephalitis, Myelitis) · Meningitis (Arachnoiditis) · PNS (Neuritis) · eye (Dacryoadenitis, Scleritis, Keratitis, Choroiditis, Retinitis, Chorioretinitis, Blepharitis, Conjunctivitis, Iritis, Uveitis) · ear (Otitis, Labyrinthitis, Mastoiditis)
Cardiovascular Carditis (Endocarditis, Myocarditis, Pericarditis) · Vasculitis (Arteritis, Phlebitis, Capillaritis)
Respiratory upper (Sinusitis, Rhinitis, Pharyngitis, Laryngitis) · lower (Tracheitis, Bronchitis, Bronchiolitis, Pneumonitis, Pleuritis) · Mediastinitis
Digestive mouth (Stomatitis, Gingivitis, Gingivostomatitis, Glossitis, Tonsillitis, Sialadenitis/Parotitis, Cheilitis, Pulpitis, Gnathitis) · tract (Esophagitis, Gastritis, Gastroenteritis, Enteritis, Colitis, Enterocolitis, Duodenitis, Ileitis, Caecitis, Appendicitis, Proctitis) · accessory (Hepatitis, Cholangitis, Cholecystitis, Pancreatitis) · Peritonitis
Integumentary Dermatitis (Folliculitis) · Cellulitis · Hidradenitis
Musculoskeletal

Arthritis · Dermatomyositis · soft tissue (Myositis, Synovitis/Tenosynovitis, Bursitis, Enthesitis, Fasciitis, Capsulitis, Epicondylitis, Tendinitis, Panniculitis)

Osteochondritis: Osteitis (Spondylitis, Periostitis) · Chondritis
Urinary Nephritis (Glomerulonephritis, Pyelonephritis) · Ureteritis · Cystitis · Urethritis
Reproductive

female: Oophoritis · Salpingitis · Endometritis · Parametritis · Cervicitis · Vaginitis · Vulvitis · Mastitis

male: Orchitis · Epididymitis · Prostatitis · Balanitis · Balanoposthitis

pregnancy/newborn: Chorioamnionitis · Omphalitis
Endocrine Insulitis · Hypophysitis · Thyroiditis · Parathyroiditis · Adrenalitis
Lymphatic Lymphangitis · Lymphadenitis
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the air spaces are almost completely replaced by carcinomatous tissue Its origin cannot be identified Note peripheral slight lymphocytic infiltrate common in and around malignant tumors

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Sat Jan 21 23:20:20 2012