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Viral Envelope Information

Many viruses (e.g. influenza and many animal viruses) have viral envelopes covering their protein capsids.[1] The envelopes typically are derived from portions of the host cell membranes (phospholipids and proteins), but include some viral glycoproteins. Functionally, viral envelopes are used to help viruses enter host cells. Glycoproteins on the surface of the envelope serve to identify and bind to receptor sites on the host's membrane. The viral envelope then fuses with the host's membrane, allowing the capsid and viral genome to enter and infect the host.

Usually, the cell from which the virus itself buds will often die or be weakened, and shed more viral particles for an extended period. The lipid bilayer envelope of these viruses is relatively sensitive to desiccation, heat and detergents, therefore these viruses are easier to sterilize than non-enveloped viruses, have limited survival outside host environments, and typically must transfer directly from host to host.

Contents

Examples

Classes of Enveloped Viruses that contain Human Pathogens:

DNA viruses

RNA viruses

Retroviruses

See also

Bacterial capsule

References

  1. ^ "CHAPTER #11: VIRUSES". http://www.slic2.wsu.edu:82/hurlbert/micro101/pages/Chap11.html. Retrieved 2008-11-07.
  2. ^ "The Rabies Virus". http://www.cdc.gov/rabies/virus.html. Retrieved 2008-11-07.

External links

· · Microbiology: Virus
Components Viral envelope · Capsid · Viral protein
Viral life cycle Viral entry · Viral replication · Viral shedding · Virus latency
Genetics Reassortment · Antigenic shift · Antigenic drift · Phenotype mixing
Other Viral disease · Laboratory diagnosis of viral infections · Viral load · Viral quantification · Antiviral drug · Bacteriophage · Neurotropic virus · Oncovirus · History of viruses

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· · Viral proteins (early and late)
DNA
Herpes simplex Herpes simplex virus protein vmw65 · HHV capsid portal protein
Hepatitis B HBsAg · HBcAg (HBeAg) · HBx · Hepatitis B virus DNA polymerase
Epstein-Barr EBNA-1 · EBNA-2 · EBNA-3 · LMP-1 · LMP-2 · EBER
RNA
Rotavirus VNPs: NSP1 · NSP2 · NSP4 · NSP5 · NSP6
Influenza

capsid: matrix protein (M1 protein) · viral envelope (M2 protein)

glycoprotein: Influenza hemagglutinin · Neuraminidase
Parainfluenza Parainfluenza hemagglutinin-neuraminidase
Mumps Mumps hemagglutinin-neuraminidase
Measles Measles hemagglutinin
RSV Respiratory syncytial virus G protein
Hepatitis C

VSPs: E1 · E2

VNPs: P7 · NS2 · NS3 · NS4 · NS5
RT
Structure and genome of HIV

VSPs: gag · pol (Integrase, Reverse transcriptase, HIV-1 protease) · env (gp120, gp41)

VRAPs: transactivators (Tat, Rev, Vpr) · Nef · Vif · Vpu
Fusion protein Gag-onc fusion protein

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Categories: Virology | Microbiology

 

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